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TN2 online lunch series - 21 January 2021
- 12.30 - 13.00 PM
Dr. Mike Wattjes (Hannover Medical School) - MRI of opportunistic infections: lessons learned in a decade using effective immunomodulatory treatments

- 13.00 - 13.30 PM
Dr. Rik Ossenkoppele (Amsterdam UMC, location Vumc) - Tau PET in aging and Alzheimer’s disease

Read more below or on our website www.tn2.eu

Contact information: conference@tn2.eu

Jan 21, 2021 12:30 PM in Amsterdam

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Mike Wattjes
Prof. dr, Neuroradiologist, Head of Imaging in Neuroinflammation @Hannover Medical School, Dept. of Neuroradiology
The approval and availability of a variety of immunosuppressive therapies has made drug-associated opportunistic infections such as progressive multifocal leukoencephalopathy (PML) an increasingly prevalent clinical entity. In addition to the clinical presentation and paraclinical tests, brain magnetic resonance imaging (MRI) is crucial for the diagnosis of drug-related adverse events, particularly with respect to an early diagnosis of opportunistic infections.
Rik Ossenkoppele
PhD @Alzheimercenter & Clinical Memory Research Unit Amsterdam UMC, location Vumc
Tau pathology is a core pathological hallmark of Alzheimer’s disease and can now be visualised and quantified in the living human brain using positron emission tomography (PET). In this lecture, I will first discuss the development and validation of novel tau PET tracers. This is followed by their application to investigate the contribution of tau pathology to the clinical and neurobiological manifestation of Alzheimer’s disease. Finally, I will provide an outlook on future neuroscientific research questions and implementation of tau PET in the clinic to optimize the diagnostic and prognostic process.