This webinar presents a framework for a gender responsive treatment approach for adult women with substance use disorders. A significant percentage of women presenting for substance use treatment often report a history of trauma as well as difficulty in developing and maintaining meaningful, healthy and sustaining relationships. Shame and fear of severe consequences may result in the denial or minimization of the existence of a problem. This in addition to society's stereotypes of women, often result in women remaining stuck in their substance use longer. These experiences further reinforce the importance of providing gender responsive and trauma informed treatment approaches. We will discuss specific treatment needs of women across the various levels of care while also describing specific clinical interventions to facilitate women's substance use treatment.