The outbreak and spread of a novel coronavirus (COVID-19) has been devastating globally, including for much of the Asia Pacific region. This unprecedented global health emergency will have profound social, psychological and economic impacts, meaning that a coordinated response is needed to address the acute and long-term mental health implications. Vulnerable people, including frontline workers, victims of domestic violence, people experiencing homelessness, substance use disorders and those with low socioeconomic status or precarious employment will be particularly at risk. Equity considerations are therefore essential when planning and implementing mental health responses. This webinar will discuss the mental health challenges resulting from the COVID-19 pandemic, will provide examples of responses from across the Asia Pacific region, and will discuss opportunities for improved mental health care access and equity, including through the use of digital technologies. The role of the APEC Digital Hub for Mental Health as a regional network responding to mental health issues in the context of COVID-19 will also be described.