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NEUR MS-20 - Shared screen with speaker view
Peter Thomas (he/him/his)
34:41
You’ve shown the rhythmic input from the rest of the network makes the prebot activity less sensitive to their internal dynamics. Would the same be true if one included rhythmic chemosensory or motor feedback input?
Christopher Wilson
36:13
Great talk Jon! I have two questions: 1) when you quantify the burstlet activity from your models, do you look at coefficient of vacation, irregularity score, or entropy measures and see how closely the burstlet variability mimics the in vitro data
Christopher Wilson
36:14
?
Tony Humphries
36:18
What happens under hypoxia?
Christopher Wilson
36:35
and 2) what IS the purpose of the pBC??
Cheng Ly
36:43
for 1st part, is it known what the difference with burstlet led oscill & non (just bursts) in relation to breathing?
Rubin, Jonathan E
42:57
The burstlets alone would not drive motor outputs. The bursts that do drive motor outputs start off as burstlets and become bursts due to successful recruitment of more neurons.
Cheng Ly
44:47
ok, thanks!
Ilya Rybak
45:50
Do you really think that you can model so complicated network with just a single cell representing the entire respiratory CPG?
Christopher Wilson
47:23
You mean ULITMATELY Ilya?? Nah, of course not!
Christopher Wilson
47:42
As Casey said, we’re developing this minimalist model to explore the dynamics
Christopher Wilson
48:34
At some point, we should chat about incorporating the full H-H model that you, Jon, and Slava have worked on so we can use the more complicated, “closer to in vivo” model to refine the work.
Christopher Wilson
51:03
Using the minimalist model, we can power through many more simulations to explore changes in alveolar oxygen, oxygen carrying capacity, etc. and then refine our simulations and “build out” to the more complicated (and representative) model.
Peter Thomas (he/him/his)
51:51
I vote for A
Rubin, Jonathan E
52:08
B
Ruizhi Hao
52:23
B
Victor Matveev
52:25
B
Peter Thomas (he/him/his)
01:24:15
Is the tail also in contact with the ground, and bearing weight during walking?
Christopher Wilson
01:38:11
You mentioned the gait being mostly a “trot” does that ever change Slava? As the animal needs to move faster, etc.?
Christopher Wilson
01:42:32
Great session!
Christopher Wilson
01:42:40
Thanks YangYang and Peter!