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Discovery Lecture - Dr. Rosen - Shared screen with speaker view
Walter Chazin
23:34
Please type questions into this chat. These can be queued up during the talk.
Charlotte Fare
54:57
if you anchor Arp/WASP to the membrane (e.g. through a flexible linker), do you see the higher normalized polymerization rates at low concentrations?
Matthew Tyska
01:15:02
In the in vitro Nephrin-Nck-WASP-ARP2/3 system, are newly polymerized actin filaments trapped in the condensates or do they escape? Thinking about their availability for integration into networks.
Ray Blind (he,his)
01:16:28
Might histone methylation stabilize chromatin LLPS or change fusing coalescing behavior?
Roger Colbran (he/him)
01:16:49
What factors determine the size of the phase-separated droplets?
Henry Ong
01:19:01
You mentioned that in condensates, higher concentration of molecules did not fully explain increase in activity - what other mechanisms do you hypothesize increase activity in condensates?
James
01:20:44
Are you able to collect a SAXS powder patterns on your DNA-condensates? I would be curious to see if you can observe spacings found in nuclei SAXS patterns.
Joel Harp
01:22:32
Just a comment from me. This is brilliant and meshes well with the “unstructured stability” hypothesis of Don and Ada Olins for chromatin domains in Open Biology 2018