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IMMU CT-3 - Shared screen with speaker view
Mohammad Islam
If you have a question for the speaker, please either type it in the chat or wait until the Q&A time after the presentation to ask your question live using the ‘Raise you hand’ reaction.
Mohammad Islam
If you have any questions for @Girma please paste it here or reach out to him.
Audrey Freischel
This was a great talk. Perhaps you mentioned it but in your phase diagrams, what does the dark blue indicate?
Solveig van der Vegt
@Audrey Freischel, Thank you! The dark blue area indicates areas of parameter space where there is only non-negative steady state, the stable origin. This is not an area of parameter space that we can reach by adding ICIs, which is why I didn’t mention it, sorry!
Farzad Fatehi Chenar
In this paper they present a simple method for model identifiability. See if it is a helpful method for your work: https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1008248
Solveig van der Vegt
@Farzad Fatehi Chenar thank you, I will have a look!
Macauley Locke
In the final slide where the probabilities have been calculated, are these from simulations?
Martin Lopez-Garcia
Thanks Macauley! They are samples from Binomial experiments. Each person who infected a dose becomes a Bernouilli experiment
Martin Lopez-Garcia
with p(Developing Disease | Dose) computed from the within-host model
Martin Lopez-Garcia
*who inhaled a dose
Macauley Locke
Ah thank you that makes sense now :)
Martin Lopez-Garcia
No questions from my side, but very nice work!
Math Dept
Thank you all!