Friday, June 26th, 2020
9:00AM - 1:00PM Eastern Time
Safety Assessment without Animals: A Real-World Case Example
Maria Baltazar and Gavin Maxwell, Unilever
Unilever scientists will lead participants through an exercise focused around conducting a NextGeneration Risk Assessment of the systemic toxicity of Coumarin in a face cream. The exercise will be split into 1) Information assessment, 2) Characterization of the bioactivity of the material, and 3) Bioactivity and metabolism refinement and decision-making. Each section will include an introduction to the section, review of the data presented in small groups, and plenary discussion of the groups' conclusions. Topics covered will include determining the decision context, weighing different types of data, and addressing uncertainty.